KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90AB2P
All Species:
45.45
Human Site:
T60
Identified Species:
76.92
UniProt:
Q58FF8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58FF8
NP_031381
381
44349
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Chimpanzee
Pan troglodytes
A5A6K9
733
84754
T65
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Rhesus Macaque
Macaca mulatta
XP_001098219
597
68451
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Dog
Lupus familis
XP_857093
509
59005
T65
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Cat
Felis silvestris
Mouse
Mus musculus
P11499
724
83307
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Rat
Rattus norvegicus
P34058
724
83263
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518700
789
90657
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Chicken
Gallus gallus
Q04619
725
83409
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
T
Frog
Xenopus laevis
NP_001086624
722
82939
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Zebra Danio
Brachydanio rerio
O57521
725
83339
T59
K
I
R
Y
E
S
L
T
D
P
T
K
L
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
L131
V
G
F
Y
S
A
Y
L
V
A
D
K
V
T
V
Honey Bee
Apis mellifera
XP_395168
718
82735
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
N
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
L131
V
G
F
Y
S
A
F
L
V
A
D
K
V
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51818
699
80034
V131
G
F
Y
S
A
Y
L
V
A
D
K
V
V
V
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
51.4
58.7
N.A.
47.2
47.5
N.A.
42.4
44.8
45
43.7
N.A.
38.4
38.1
36.1
N.A.
Protein Similarity:
100
47.3
55.7
67.5
N.A.
49.8
50
N.A.
45.2
48.5
48.4
48.6
N.A.
45.1
44.4
45.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
13.3
93.3
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
26.6
100
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
0
0
8
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
79
8
15
0
0
79
0
% D
% Glu:
0
0
0
0
79
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
15
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
79
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
79
0
0
0
0
0
0
0
0
0
8
93
0
0
0
% K
% Leu:
0
0
0
0
0
0
86
15
0
0
0
0
79
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
79
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
79
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
15
79
0
0
0
0
72
0
0
0
65
% S
% Thr:
0
0
0
0
0
0
0
79
0
0
8
0
0
8
15
% T
% Val:
15
0
0
0
0
0
0
8
15
0
0
8
22
15
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
93
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _